HRH2

Across TCGA patient cohorts, HRH2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,029 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HRH2-associated genes across cancer lineages are APOBEC3H, FOXRED2, and KIAA0930. Each is linked with HRH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HRH2-to-partner and partner-to-HRH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HRH2 versus APOBEC3H in GBM, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRH2→partner) and Y-score (partner→HRH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APOBEC3H →	-0.543	-0.676	.003	.001	3	1
GBM	FOXRED2 →	+1.035	+0.867	.002	.001	3	1
GBM	KIAA0930 →	-0.912	-0.829	.002	.003	3	1
GBM	NCF4 →	-0.995	-0.618	.008	.005	3	1
GBM	CSF2RB →	-1.239	-0.905	.003	.001	3	1
GBM	GZMH →	-1.079	-0.625	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,029 associations by consensus.

HRH2 vs APOBEC3H — GBM

Explore this scatter interactively →