HRH2

Across TCGA cell cohorts, HRH2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible HRH2-associated genes across cancer lineages are MMD2 and OR13C5. Each is linked with HRH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HRH2-to-partner and partner-to-HRH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMD2 grouped by HRH2-low versus HRH2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRH2→partner) and Y-score (partner→HRH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	MMD2 →	+0.063	+5.087	<.001	.004	3	1
URINARY_TRACT	OR13C5 →	+0.760	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MMD2 by HRH2 expression — URINARY_TRACT

Explore this box plot interactively →