Across TCGA patient cohorts, HRH1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,330 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HRH1-associated genes across cancer lineages are RAB11FIP4, EMP1, and TIGD3. Each is linked with HRH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HRH1-to-partner and partner-to-HRH1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRH1→partner) and Y-score (partner→HRH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAB11FIP4 →	-0.729	-0.390	<.001	<.001	3	2
GBM	EMP1 →	+1.133	+0.657	<.001	<.001	3	2
LSCC	TIGD3 →	-0.633	-0.433	.001	.007	3	2
LSCC	TPI1P3 →	-0.719	-0.446	.005	.003	3	2
GBM	RNF220 →	-0.397	-0.528	.004	<.001	3	2
GBM	PTMA →	-0.362	-0.396	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,330 associations by consensus.

Exploration

HRH1 survival (RNA) · tumor vs normal (RNA) · all HRH1 data types