HRG

Across TCGA patient cohorts, HRG RNA expression is significantly associated with the protein abundance of many other proteins, with 7,007 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HRG-associated proteins across cancer lineages are KRT6A, MTFR1L, and RCSD1_S108. Each is linked with HRG in more than 1 cancer types. Because this analysis shows association rather than direction, both HRG-to-partner and partner-to-HRG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HRG versus KRT6A in LSCC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HRG→partner) and Y-score (partner→HRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KRT6A →	+1.302	+0.154	<.001	.001	3	2
OV	MTFR1L →	-0.331	-0.152	<.001	.004	3	2
LSCC	RCSD1_S108 →	-1.117	-0.256	<.001	.002	3	2
GBM	SELPLG_S389 →	-0.556	-0.018	<.001	.003	3	2
LSCC	SH3KBP1_S503 →	-0.684	-0.146	<.001	<.001	3	2
LSCC	SLAIN1 →	-0.383	-0.144	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,007 associations by consensus.

HRG vs KRT6A — LSCC

Explore this scatter interactively →