HRAS

Across TCGA cell cohorts, HRAS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,675 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HRAS-associated GO terms across cancer lineages are CTP salvage, Positive regulation of DNA-templated DNA replication, and Protein depolymerization. Each is linked with HRAS in more than 10 cancer types. Because this analysis shows association rather than direction, both HRAS-to-partner and partner-to-HRAS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by HRAS-low versus HRAS-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HRAS→partner) and Y-score (partner→HRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CTP salvage →	+0.190	+1.147	<.001	<.001	3	11
PANCREAS	Positive regulation of DNA-templated DNA replication →	+0.080	+0.710	<.001	<.001	3	10
STOMACH	Protein depolymerization →	+0.096	+1.140	<.001	<.001	3	10
URINARY_TRACT	Telomere tethering at nuclear periphery →	+0.186	+1.567	<.001	<.001	3	10
STOMACH	Response to oscillatory fluid shear stress →	+0.119	+0.696	.006	.007	3	10
STOMACH	Cellular response to oscillatory fluid shear stress →	+0.119	+0.696	.006	.007	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,675 associations by consensus.

CTP salvage by HRAS expression — STOMACH

Explore this box plot interactively →