HRAS

Across TCGA cell cohorts, HRAS protein abundance is significantly associated with the RNA expression of many other genes, with 2,960 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HRAS-associated genes across cancer lineages are SLC22A4, PRNP, and TSSC4. Each is linked with HRAS in more than 7 cancer types. Because this analysis shows association rather than direction, both HRAS-to-partner and partner-to-HRAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HRAS versus SLC22A4 in BLOOD_Lymphoma, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRAS→partner) and Y-score (partner→HRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC22A4 →	+1.514	+1.261	.006	<.001	3	8
BLOOD_Lymphoma	PRNP →	+2.822	+1.279	.001	.004	3	5
OESOPHAGUS	TSSC4 →	+0.891	+1.214	.003	.002	3	5
URINARY_TRACT	RHOG →	+1.242	+1.578	<.001	.002	3	5
BLOOD_Lymphoma	CD274 →	+4.118	+1.215	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	AP5S1 →	+0.678	+0.698	.001	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,960 associations by consensus.

HRAS vs SLC22A4 — BLOOD_Lymphoma

Explore this scatter interactively →