HRAS

Across TCGA cell cohorts, HRAS protein abundance is significantly associated with the go_rna of many other GO terms, with 1,484 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HRAS-associated GO terms across cancer lineages are tRNA aminoacylation for mitochondrial protein translation, Short-chain fatty acid catabolic process, and Glycolipid catabolic process. Each is linked with HRAS in more than 4 cancer types. Because this analysis shows association rather than direction, both HRAS-to-partner and partner-to-HRAS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA aminoacylation for mitochondrial protein translation grouped by HRAS-low versus HRAS-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HRAS→partner) and Y-score (partner→HRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	tRNA aminoacylation for mitochondrial protein translation →	-0.110	-1.288	.002	.007	3	4
LARGE_INTESTINE	Short-chain fatty acid catabolic process →	-0.121	-0.777	.002	.004	3	4
BLOOD_Lymphoma	Glycolipid catabolic process →	+0.176	+1.408	.002	.002	3	4
BLOOD_Lymphoma	Regulation of double-strand break repair via nonhomologous end joining →	-0.100	-1.573	<.001	<.001	3	4
BLOOD_Lymphoma	Positive regulation of DNA repair →	-0.055	-1.697	.009	.002	2	5
OESOPHAGUS	Negative regulation of T-helper 2 cell differentiation →	+0.108	+0.990	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,484 associations by consensus.

tRNA aminoacylation for mitochondrial protein translation by HRAS expression — BLOOD_Lymphoma

Explore this box plot interactively →