Across TCGA cell cohorts, HPDL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,923 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HPDL-associated GO terms across cancer lineages are 'de novo' UMP biosynthetic process, Mitochondrial potassium ion transmembrane transport, and Ribosomal large subunit assembly. Each is linked with HPDL in more than 7 cancer types. Because this analysis shows association rather than direction, both HPDL-to-partner and partner-to-HPDL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HPDL→partner) and Y-score (partner→HPDL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	'de novo' UMP biosynthetic process →	+0.066	+1.162	.009	.003	3	8
OVARY	Mitochondrial potassium ion transmembrane transport →	+0.114	+1.663	<.001	<.001	3	7
BONE	Ribosomal large subunit assembly →	+0.119	+1.749	.002	.004	3	7
BONE	Ribosome assembly →	+0.089	+1.783	.001	.003	2	8
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.114	+1.137	<.001	.008	3	7
UPPER_AERODIGESTIVE_TRACT	Nucleoside triphosphate biosynthetic process →	+0.068	+1.088	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,923 associations by consensus.

Exploration

HPDL survival (RNA) · tumor vs normal (RNA) · all HPDL data types