HPCAL4

Across TCGA patient cohorts, HPCAL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,374 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HPCAL4-associated proteins across cancer lineages are DCLK1, CACNA2D1, and EEF2_S502. Each is linked with HPCAL4 in more than 4 cancer types. Because this analysis shows association rather than direction, both HPCAL4-to-partner and partner-to-HPCAL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HPCAL4 versus DCLK1 in CCRCC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HPCAL4→partner) and Y-score (partner→HPCAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DCLK1 →	+0.816	+0.630	<.001	.006	3	5
GBM	CACNA2D1 →	+1.015	+2.387	<.001	<.001	3	4
PDAC	EEF2_S502 →	-0.861	-0.303	<.001	<.001	3	4
GBM	KIF3A →	+0.302	+1.609	<.001	<.001	3	4
CCRCC	NCAM1 →	+0.832	+0.792	<.001	.002	3	4
GBM	PPP1R1A_S67 →	+0.757	+1.322	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,374 associations by consensus.

HPCAL4 vs DCLK1 — CCRCC

Explore this scatter interactively →