HPCAL4

Across TCGA cell cohorts, HPCAL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,197 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HPCAL4-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Protein-RNA complex assembly, and RNA splicing, via transesterification reactions. Each is linked with HPCAL4 in more than 11 cancer types. Because this analysis shows association rather than direction, both HPCAL4-to-partner and partner-to-HPCAL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, cytochrome c to oxygen grouped by HPCAL4-low versus HPCAL4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HPCAL4→partner) and Y-score (partner→HPCAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.121	+1.070	<.001	.001	3	12
OESOPHAGUS	Protein-RNA complex assembly →	+0.070	+0.932	.001	.005	3	11
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.058	+0.788	.003	.001	3	11
OESOPHAGUS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.056	+0.788	.003	.001	3	11
OESOPHAGUS	mRNA splicing, via spliceosome →	+0.056	+0.788	.003	.001	3	11
OESOPHAGUS	Cytoplasmic translation →	+0.153	+1.372	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,197 associations by consensus.

Mitochondrial electron transport, cytochrome c to oxygen by HPCAL4 expression — OESOPHAGUS

Explore this box plot interactively →