HPCAL1

Across TCGA patient cohorts, HPCAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,316 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HPCAL1-associated genes across cancer lineages are CBX7, EMP3, and MMP28. Each is linked with HPCAL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HPCAL1-to-partner and partner-to-HPCAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HPCAL1 versus CBX7 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HPCAL1→partner) and Y-score (partner→HPCAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CBX7 →	+0.592	+0.536	<.001	<.001	3	5
UCEC	EMP3 →	+0.651	+0.373	.001	.001	3	4
LUAD	MMP28 →	+1.296	+0.300	.001	<.001	3	4
GBM	PDE1B →	+0.529	+0.343	<.001	<.001	3	4
GBM	GFRA2 →	+0.713	+0.303	<.001	<.001	3	4
CCRCC	KCNK3 →	+0.930	+0.337	.004	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,316 associations by consensus.

HPCAL1 vs CBX7 — UCEC

Explore this scatter interactively →