HOXD4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HOXD4 protein abundance is significantly associated with the RNA expression of many other genes, with 642 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HOXD4-associated genes across cancer lineages are KAT5, KBTBD3, and RNF5. Each is linked with HOXD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXD4-to-partner and partner-to-HOXD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXD4 versus KAT5 in CCRCC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD4→partner) and Y-score (partner→HOXD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCKAT5 →+0.469+1.327<.001<.00132
OVKBTBD3 →+0.534+1.262.004.00132
CCRCCRNF5 →+0.583+0.818.003.00732
OVHAGLR →+2.387+1.713<.001<.00132
OVZNF503-AS1 →+1.826+1.834.001<.00132
OVHAGLROS →+1.656+1.477.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 642 associations by consensus.

HOXD4 vs KAT5 — CCRCC

Per-sample scatter of HOXD4 vs KAT5 in CCRCC (Pearson r = 0.55).

Explore this scatter interactively →

Exploration