HOXD3

Across TCGA cell cohorts, HOXD3 RNA expression is significantly associated with the RNA expression of many other genes, with 7,170 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOXD3-associated genes across cancer lineages are HOXD4, HOXD8, and HOXD9. Each is linked with HOXD3 in more than 19 cancer types. Because this analysis shows association rather than direction, both HOXD3-to-partner and partner-to-HOXD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXD3 versus HOXD4 in BONE, with a Pearson correlation of 0.78.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD3→partner) and Y-score (partner→HOXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	HOXD4 →	+1.681	+1.312	<.001	<.001	3	20
KIDNEY	HOXD8 →	+2.048	+1.269	<.001	<.001	3	15
KIDNEY	HOXD9 →	+2.346	+1.337	<.001	<.001	3	11
SOFT_TISSUE	HOXD1 →	+1.440	+1.489	.001	<.001	3	8
BONE	HOXD11 →	+2.516	+1.243	<.001	<.001	3	7
KIDNEY	HOXD10 →	+2.957	+1.075	<.001	.002	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,170 associations by consensus.

HOXD3 vs HOXD4 — BONE

Explore this scatter interactively →