HOXD3

Across TCGA cell cohorts, HOXD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,879 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOXD3-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, ATP metabolic process, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with HOXD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both HOXD3-to-partner and partner-to-HOXD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by HOXD3-low versus HOXD3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD3→partner) and Y-score (partner→HOXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleoside triphosphate metabolic process →	+0.081	+1.266	<.001	<.001	3	8
BONE	ATP metabolic process →	+0.080	+1.211	<.001	<.001	3	7
OESOPHAGUS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.104	+0.579	<.001	.004	2	8
BONE	Purine nucleoside triphosphate metabolic process →	+0.077	+1.118	<.001	<.001	3	7
BONE	Purine ribonucleoside triphosphate metabolic process →	+0.076	+1.211	<.001	<.001	3	7
OESOPHAGUS	Regulation of myoblast fusion →	+0.104	+0.769	.003	.004	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,879 associations by consensus.

Nucleoside triphosphate metabolic process by HOXD3 expression — BONE

Explore this box plot interactively →