HOXD13

Across TCGA patient cohorts, HOXD13 protein abundance is significantly associated with the RNA expression of many other genes, with 8,088 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HOXD13-associated genes across cancer lineages are TOM1, PIK3R2, and KLRB1. Each is linked with HOXD13 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXD13-to-partner and partner-to-HOXD13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXD13 versus TOM1 in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD13→partner) and Y-score (partner→HOXD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TOM1 →	+0.422	+0.390	.007	.004	3	1
LSCC	PIK3R2 →	-0.154	-0.470	.003	.005	3	1
LSCC	KLRB1 →	-0.723	-0.378	.004	.002	3	1
LSCC	CD244 →	-1.087	-0.507	.009	.004	3	1
LSCC	RTN2 →	+0.651	+0.372	.004	.007	3	1
LSCC	TXLNGY →	-2.397	-0.378	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,088 associations by consensus.

HOXD13 vs TOM1 — LSCC

Explore this scatter interactively →