HOXD13

Across TCGA cell cohorts, HOXD13 RNA expression is significantly associated with the RNA expression of many other genes, with 6,902 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOXD13-associated genes across cancer lineages are HOXD10, HOXD11, and HOXD9. Each is linked with HOXD13 in more than 10 cancer types. Because this analysis shows association rather than direction, both HOXD13-to-partner and partner-to-HOXD13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXD13 versus HOXD10 in BONE, with a Pearson correlation of 0.83.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD13→partner) and Y-score (partner→HOXD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	HOXD10 →	+3.414	+3.697	<.001	<.001	3	11
BONE	HOXD11 →	+3.472	+3.846	<.001	<.001	3	11
LUNG_NSCLC_LUSC	HOXD9 →	+2.569	+2.166	<.001	<.001	3	9
BONE	HOXD12 →	+0.708	+3.401	.002	<.001	2	9
SOFT_TISSUE	HOXD8 →	+1.885	+1.705	<.001	<.001	3	8
BONE	ALX1 →	+2.164	+3.539	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,902 associations by consensus.

HOXD13 vs HOXD10 — BONE

Explore this scatter interactively →