HOXC8

Across TCGA patient cohorts, HOXC8 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,326 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HOXC8-associated proteins across cancer lineages are MYL9, HOXC10_S189, and VIM_S214. Each is linked with HOXC8 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOXC8-to-partner and partner-to-HOXC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXC8 versus MYL9 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC8→partner) and Y-score (partner→HOXC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYL9 →	+0.567	+1.126	<.001	<.001	3	5
LUAD	HOXC10_S189 →	+1.661	+1.624	<.001	<.001	3	5
PDAC	VIM_S214 →	+0.526	+0.505	<.001	<.001	3	4
BRCA	LMCD1 →	+0.428	+0.650	<.001	<.001	3	4
BRCA	LUM →	+0.804	+0.646	<.001	<.001	3	4
BRCA	MFAP5 →	+0.423	+0.719	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,326 associations by consensus.

HOXC8 vs MYL9 — BRCA

Explore this scatter interactively →