Across TCGA patient cohorts, HOXC4 mutation is significantly associated with the RNA expression of many other genes, with 371 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOXC4-associated genes across cancer lineages are RN7SL803P, SNORD66, and OR5T2. Each is linked with HOXC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both HOXC4-to-partner and partner-to-HOXC4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC4→partner) and Y-score (partner→HOXC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SL803P →	+0.226	+4.480	<.001	.005	3	3
HNSC	SNORD66 →	+0.538	+4.565	<.001	.004	3	2
CESC	OR5T2 →	+0.032	+5.164	<.001	.002	3	2
CESC	STMN1P2 →	+0.057	+3.612	.003	.006	3	2
LIHC	TYMSP2 →	+0.146	+5.033	<.001	.009	3	2
LIHC	BNIP3P31 →	+0.212	+5.033	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

Exploration

HOXC4 survival (RNA) · tumor vs normal (RNA) · all HOXC4 data types