HOXC4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HOXC4 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOXC4-associated genes across cancer lineages are p90 RSK and Chk1_pS345. Each is linked with HOXC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXC4-to-partner and partner-to-HOXC4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC4→partner) and Y-score (partner→HOXC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECp90 RSK →+0.294+3.183.005.01031
UCECChk1_pS345 →+0.173+3.183.022.01011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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