HOXC13

Across TCGA patient cohorts, HOXC13 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,501 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HOXC13-associated proteins across cancer lineages are HOXC10_S189, DIP2B, and RHOB. Each is linked with HOXC13 in more than 3 cancer types. Because this analysis shows association rather than direction, both HOXC13-to-partner and partner-to-HOXC13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXC13 versus HOXC10_S189 in LSCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC13→partner) and Y-score (partner→HOXC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HOXC10_S189 →	+1.838	+1.080	<.001	<.001	3	4
LSCC	DIP2B →	+0.522	+0.754	<.001	<.001	3	3
LSCC	RHOB →	+0.620	+0.911	<.001	<.001	3	3
LSCC	KRT14 →	+1.508	+0.738	<.001	<.001	3	3
HNSC	KRT16 →	+1.088	+0.700	<.001	.001	3	3
LSCC	MBP →	-0.264	-0.728	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,501 associations by consensus.

HOXC13 vs HOXC10_S189 — LSCC

Explore this scatter interactively →