HOXC11

Across TCGA patient cohorts, HOXC11 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,226 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HOXC11-associated proteins across cancer lineages are HOXC10_S189, GPSM1_S493, and TBC1D17. Each is linked with HOXC11 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOXC11-to-partner and partner-to-HOXC11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXC11 versus HOXC10_S189 in UCEC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC11→partner) and Y-score (partner→HOXC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HOXC10_S189 →	+1.646	+1.466	<.001	<.001	3	5
BRCA	GPSM1_S493 →	+0.878	+1.557	<.001	<.001	3	4
COAD	TBC1D17 →	-0.185	-0.905	.008	.001	3	3
BRCA	TMEM159 →	+0.572	+1.119	.002	.003	3	3
LSCC	SMARCA1 →	+0.468	+0.731	<.001	.001	3	3
LSCC	ZCRB1 →	+0.252	+0.740	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,226 associations by consensus.

HOXC11 vs HOXC10_S189 — UCEC

Explore this scatter interactively →