HOXC11

Across TCGA cell cohorts, HOXC11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,231 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOXC11-associated GO terms across cancer lineages are Embryonic skeletal joint morphogenesis, Embryonic skeletal joint development, and Response to testosterone. Each is linked with HOXC11 in more than 10 cancer types. Because this analysis shows association rather than direction, both HOXC11-to-partner and partner-to-HOXC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic skeletal joint morphogenesis grouped by HOXC11-low versus HOXC11-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC11→partner) and Y-score (partner→HOXC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Embryonic skeletal joint morphogenesis →	-0.336	-1.784	<.001	<.001	3	11
BLOOD_Lymphoma	Embryonic skeletal joint development →	-0.281	-0.951	<.001	<.001	3	9
PANCREAS	Response to testosterone →	-0.115	-1.047	<.001	.001	2	8
UPPER_AERODIGESTIVE_TRACT	Fatty acid beta-oxidation →	+0.100	+1.030	<.001	<.001	3	6
BONE	mRNA transcription by RNA polymerase II →	+0.093	+2.307	.002	.001	3	6
CNS	Indole-containing compound biosynthetic process →	-0.469	-0.671	.007	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,231 associations by consensus.

Embryonic skeletal joint morphogenesis by HOXC11 expression — SOFT_TISSUE

Explore this box plot interactively →