HOXB9

Across TCGA cell cohorts, HOXB9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,612 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HOXB9-associated GO terms across cancer lineages are Proximal/distal pattern formation, Formate metabolic process, and Heart valve formation. Each is linked with HOXB9 in more than 9 cancer types. Because this analysis shows association rather than direction, both HOXB9-to-partner and partner-to-HOXB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proximal/distal pattern formation grouped by HOXB9-low versus HOXB9-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB9→partner) and Y-score (partner→HOXB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Proximal/distal pattern formation →	+1.854	+3.471	<.001	<.001	3	10
BLOOD_Leukemia	Formate metabolic process →	+0.084	+1.848	<.001	<.001	3	8
BONE	Heart valve formation →	-0.213	-2.813	<.001	<.001	3	8
KIDNEY	Anterior/posterior pattern specification →	+0.049	+2.169	.006	<.001	3	7
URINARY_TRACT	Positive regulation of axon guidance →	+1.054	+1.964	<.001	<.001	3	6
CNS	Proteinogenic amino acid biosynthetic process →	+0.066	+1.360	.005	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,612 associations by consensus.

Proximal/distal pattern formation by HOXB9 expression — BLOOD_Lymphoma

Explore this box plot interactively →