HOXB4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HOXB4 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible HOXB4-associated genes across cancer lineages are GMP. Each is linked with HOXB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXB4-to-partner and partner-to-HOXB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by HOXB4-low versus HOXB4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB4→partner) and Y-score (partner→HOXB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAGMP →+0.082+2.738.014.01731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GMP by HOXB4 expression — BLCA

Box plot of GMP in HOXB4-low vs HOXB4-high samples in BLCA.

Explore this box plot interactively →

Exploration