HOXB2

Across TCGA patient cohorts, HOXB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,952 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HOXB2-associated proteins across cancer lineages are CEBPZ, PRKD1_S249, and HOXB4. Each is linked with HOXB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both HOXB2-to-partner and partner-to-HOXB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB2 versus CEBPZ in BRCA, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB2→partner) and Y-score (partner→HOXB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CEBPZ →	-0.554	-1.687	<.001	<.001	3	6
PDAC	PRKD1_S249 →	+0.874	+0.702	<.001	<.001	3	5
UCEC	HOXB4 →	+1.100	+2.140	.001	<.001	3	5
LSCC	PPIF →	-0.685	-0.863	<.001	<.001	3	5
COAD	DPYSL3 →	+0.526	+0.766	.001	<.001	3	5
BRCA	GDI1 →	+0.324	+1.435	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,952 associations by consensus.

HOXB2 vs CEBPZ — BRCA

Explore this scatter interactively →