Across TCGA patient cohorts, HOXA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,896 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HOXA4-associated proteins across cancer lineages are HOXA3_S184, HOXA4_S109, and A1BG. Each is linked with HOXA4 in more than 7 cancer types. Because this analysis shows association rather than direction, both HOXA4-to-partner and partner-to-HOXA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA4→partner) and Y-score (partner→HOXA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HOXA3_S184 →	+1.849	+1.113	<.001	<.001	3	8
OV	HOXA4_S109 →	+2.198	+0.805	<.001	<.001	3	6
BRCA	A1BG →	+0.423	+0.224	.001	.001	3	4
UCEC	SLFN5 →	-0.275	-0.476	.001	.004	3	3
UCEC	AHNAK_T2845 →	+0.966	+0.525	<.001	.001	3	3
PDAC	FETUB →	+0.503	+0.161	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,896 associations by consensus.

Exploration

HOXA4 survival (RNA) · tumor vs normal (RNA) · all HOXA4 data types