HOXA3

Across TCGA patient cohorts, HOXA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,198 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HOXA3-associated proteins across cancer lineages are HOXA3_S184, HOXA4_S109, and A1BG. Each is linked with HOXA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both HOXA3-to-partner and partner-to-HOXA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXA3 versus HOXA3_S184 in UCEC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA3→partner) and Y-score (partner→HOXA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HOXA3_S184 →	+2.507	+1.679	<.001	<.001	3	8
OV	HOXA4_S109 →	+1.908	+1.449	<.001	.001	3	5
BRCA	A1BG →	+0.569	+0.681	<.001	<.001	3	4
BRCA	DPYSL3 →	+0.629	+0.518	<.001	<.001	3	4
CCRCC	FOXK1 →	+0.231	+0.604	<.001	<.001	3	4
OV	AGT →	+0.622	+0.846	.007	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,198 associations by consensus.

HOXA3 vs HOXA3_S184 — UCEC

Explore this scatter interactively →