HOXA2

Across TCGA cell cohorts, HOXA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,568 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible HOXA2-associated GO terms across cancer lineages are RNA localization, Protein stabilization, and Regulation of telomerase RNA localization to Cajal body. Each is linked with HOXA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both HOXA2-to-partner and partner-to-HOXA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by HOXA2-low versus HOXA2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA2→partner) and Y-score (partner→HOXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RNA localization →	+0.081	+0.998	<.001	<.001	3	10
STOMACH	Protein stabilization →	+0.077	+1.568	<.001	.002	3	10
BREAST	Regulation of telomerase RNA localization to Cajal body →	+0.082	+0.713	<.001	.001	3	9
URINARY_TRACT	Regulation of myoblast fusion →	+0.079	+0.973	<.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.092	+0.751	.003	.004	3	9
BONE	Regulation of focal adhesion assembly →	+0.126	+0.440	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,568 associations by consensus.

RNA localization by HOXA2 expression — SKIN

Explore this box plot interactively →