HOXA13

Across TCGA cell cohorts, HOXA13 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,410 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOXA13-associated GO terms across cancer lineages are Embryonic hindgut morphogenesis, Regulation of bone mineralization, and Peroxisome proliferator activated receptor signaling pathway. Each is linked with HOXA13 in more than 7 cancer types. Because this analysis shows association rather than direction, both HOXA13-to-partner and partner-to-HOXA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic hindgut morphogenesis grouped by HOXA13-low versus HOXA13-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA13→partner) and Y-score (partner→HOXA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Embryonic hindgut morphogenesis →	+1.369	+2.164	<.001	<.001	3	8
LARGE_INTESTINE	Regulation of bone mineralization →	+0.033	+1.130	.003	.008	3	7
PANCREAS	Peroxisome proliferator activated receptor signaling pathway →	+0.073	+1.747	.001	<.001	3	6
LARGE_INTESTINE	Hindgut development →	+1.267	+1.949	<.001	<.001	3	6
LARGE_INTESTINE	Hindgut morphogenesis →	+1.267	+1.949	<.001	<.001	3	6
SOFT_TISSUE	Mesodermal cell fate specification →	+1.366	+0.994	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,410 associations by consensus.

Embryonic hindgut morphogenesis by HOXA13 expression — LARGE_INTESTINE

Explore this box plot interactively →