HOXA13

Across TCGA cell cohorts, HOXA13 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HOXA13-associated genes across cancer lineages are UTF1 and CHAT. Each is linked with HOXA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXA13-to-partner and partner-to-HOXA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UTF1 grouped by HOXA13-low versus HOXA13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA13→partner) and Y-score (partner→HOXA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UTF1 →	+0.028	+5.217	<.001	<.001	3	1
LARGE_INTESTINE	CHAT →	+0.035	+4.273	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

UTF1 by HOXA13 expression — LARGE_INTESTINE

Explore this box plot interactively →