HOOK2

Across TCGA cell cohorts, HOOK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,845 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HOOK2-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Flagellated sperm motility. Each is linked with HOOK2 in more than 18 cancer types. Because this analysis shows association rather than direction, both HOOK2-to-partner and partner-to-HOOK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by HOOK2-low versus HOOK2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOOK2→partner) and Y-score (partner→HOOK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.128	-1.762	<.001	.005	3	19
OESOPHAGUS	Cilium-dependent cell motility →	-0.128	-1.762	<.001	.005	3	19
URINARY_TRACT	Flagellated sperm motility →	-0.116	-1.586	.001	<.001	3	18
URINARY_TRACT	Cilium movement involved in cell motility →	-0.112	-1.789	<.001	<.001	3	18
URINARY_TRACT	Sperm motility →	-0.116	-1.586	.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.113	+1.218	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,845 associations by consensus.

Cilium or flagellum-dependent cell motility by HOOK2 expression — OESOPHAGUS

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