HOMER2

Across TCGA patient cohorts, HOMER2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,850 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HOMER2-associated proteins across cancer lineages are RBP1, STK17B, and CA12. Each is linked with HOMER2 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOMER2-to-partner and partner-to-HOMER2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOMER2 versus RBP1 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOMER2→partner) and Y-score (partner→HOMER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RBP1 →	+1.001	+0.753	<.001	<.001	3	5
LSCC	STK17B →	-0.374	-0.693	<.001	.005	3	4
BRCA	CA12 →	+0.849	+0.770	.001	<.001	3	4
BRCA	DDAH1 →	+0.486	+0.573	<.001	<.001	3	4
OV	EFL1 →	+0.261	+0.699	.001	<.001	3	4
UCEC	FBXO22 →	+0.263	+1.179	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,850 associations by consensus.

HOMER2 vs RBP1 — HNSC

Explore this scatter interactively →