HOMER2

Across TCGA patient cohorts, HOMER2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,572 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOMER2-associated genes across cancer lineages are NCAPH, SNORD65C, and LINC02588. Each is linked with HOMER2 in more than 3 cancer types. Because this analysis shows association rather than direction, both HOMER2-to-partner and partner-to-HOMER2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOMER2 versus NCAPH in HNSC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOMER2→partner) and Y-score (partner→HOMER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NCAPH →	-0.658	-0.435	<.001	<.001	3	4
UCEC	SNORD65C →	-1.597	-0.384	<.001	<.001	3	4
GBM	LINC02588 →	-0.946	-0.276	.001	.005	3	4
UCEC	HOXA2 →	-0.920	-0.464	<.001	<.001	3	3
UCEC	HOXA3 →	-0.942	-0.366	<.001	<.001	3	3
UCEC	KLHL2 →	+0.730	+0.622	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,572 associations by consensus.

HOMER2 vs NCAPH — HNSC

Explore this scatter interactively →