HOGA1

Across TCGA patient cohorts, HOGA1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,614 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HOGA1-associated genes across cancer lineages are RAE1, PRELID3B, and PSMA7. Each is linked with HOGA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOGA1-to-partner and partner-to-HOGA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOGA1 versus RAE1 in PDAC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOGA1→partner) and Y-score (partner→HOGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RAE1 →	-0.211	-0.754	.008	.001	3	2
GBM	PRELID3B →	-0.390	-0.578	.009	.004	3	2
PDAC	PSMA7 →	-0.284	-0.659	<.001	.006	3	2
PDAC	P2RX1 →	+0.798	+0.798	<.001	<.001	3	2
PDAC	PSMD14 →	-0.308	-0.726	.001	.002	3	2
GBM	SUMO1 →	-0.327	-0.876	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,614 associations by consensus.

HOGA1 vs RAE1 — PDAC

Explore this scatter interactively →