HOGA1

Across TCGA cell cohorts, HOGA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,738 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOGA1-associated GO terms across cancer lineages are Glyoxylate catabolic process, Trans-4-hydroxy-L-proline catabolic process, and Glyoxylate metabolic process. Each is linked with HOGA1 in more than 18 cancer types. Because this analysis shows association rather than direction, both HOGA1-to-partner and partner-to-HOGA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glyoxylate catabolic process grouped by HOGA1-low versus HOGA1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOGA1→partner) and Y-score (partner→HOGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Glyoxylate catabolic process →	+1.734	+2.783	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Trans-4-hydroxy-L-proline catabolic process →	-0.191	-1.077	.001	.002	3	10
LUNG_NSCLC_LUAD	Glyoxylate metabolic process →	-0.231	-0.712	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Pyruvate biosynthetic process →	-0.118	-0.969	<.001	<.001	3	7
BONE	Regulation of lipid biosynthetic process →	+0.078	+0.901	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Methylglyoxal metabolic process →	+0.152	+1.167	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,738 associations by consensus.

Glyoxylate catabolic process by HOGA1 expression — KIDNEY

Explore this box plot interactively →