Across TCGA pan-cancer cohorts, HNRNPUL2 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated HNRNPUL2 data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher HNRNPUL2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated HNRNPUL2 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

CESC, PRAD, and SARC are the cancer types where HNRNPUL2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	II,III,IV	0.068	0.830	<.001	24	view →
PRAD	OS	Median	All	0.145	0.883	<.001	12	view →
SARC	DFS	Median	All	0.095	0.632	.002	6	view →
BLCA	OS	Median	II,III,IV	1.000	0.699	.016	5	view →
THCA	OS	Median	All	0.342	0.955	<.001	3	view →
COAD	OS	Median	II,III,IV	0.327	0.792	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: HNRNPUL2 tumor-vs-normal RNA expression · all HNRNPUL2 data types