Across TCGA pan-cancer cohorts, HNRNPUL2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HNRNPUL2 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher HNRNPUL2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated HNRNPUL2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

PDAC, HNSC, and GBM are the cancer types where HNRNPUL2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	III,IV	0.199	0.557	.012	7	view →
HNSC	DFS	Median	II,III,IV	0.746	0.570	.043	4	view →
GBM	OS	Quartile	All	0.546	0.286	.009	3	view →
CCRCC	OS	Median	III,IV	1.000	0.831	.029	2	view →
LSCC	OS	Median	II,III,IV	0.810	1.000	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: HNRNPUL2 tumor-vs-normal RNA expression · all HNRNPUL2 data types