HNRNPUL2-BSCL2

Across TCGA pan-cancer cohorts, HNRNPUL2-BSCL2 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of HNRNPUL2-BSCL2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where HNRNPUL2-BSCL2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HNRNPUL2-BSCL2 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

HNSC, THCA, and LIHC are the cancer types where HNRNPUL2-BSCL2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HNRNPUL2-BSCL2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.329	<.001	11	view →
THCA	All	II,III,IV	−0.343	.003	6	view →
LIHC	Female	All	+0.209	<.001	6	view →
LUSC	All	All	+0.228	.001	4	view →
KIRC	All	All	+0.137	.003	4	view →
CHOL	All	All	+0.385	<.001	3	view →
KIRP	Female	II,III,IV	+0.316	.018	3	view →
COAD	Female	All	−0.262	.021	3	view →
BLCA	All	All	+0.162	.017	3	view →
STAD	Male	II,III,IV	+0.451	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

HNRNPUL2-BSCL2–HNSC

Open the HNSC breakdown →