HNRNPUL1

Across TCGA pan-cancer cohorts, HNRNPUL1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated HNRNPUL1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher HNRNPUL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HNRNPUL1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

HNSC, UCEC, and CCRCC are the cancer types where HNRNPUL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	II,III,IV	0.788	0.990	.001	35	view →
UCEC	DFS	Median	III,IV	0.499	0.914	.015	16	view →
CCRCC	DFS	Tertile	All	0.465	0.919	.014	13	view →
OV	DFS	Quartile	All	0.590	0.950	.030	8	view →
LUAD	OS	Median	II,III,IV	0.906	0.342	.005	6	view →
GBM	DFS	Quartile	All	0.486	0.330	.039	4	view →
PDAC	DFS	Median	All	0.831	0.693	.020	3	view →
LSCC	DFS	Median	II,III,IV	0.451	0.877	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

HNRNPUL1–HNSC (OS)

Open the HNSC breakdown →