HNRNPUL1

Across TCGA patient cohorts, HNRNPUL1 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPUL1-associated genes across cancer lineages are MEK1, mTOR, and ATM. Each is linked with HNRNPUL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPUL1-to-partner and partner-to-HNRNPUL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by HNRNPUL1-low versus HNRNPUL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPUL1→partner) and Y-score (partner→HNRNPUL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.397	+3.807	<.001	<.001	3	2
UCEC	mTOR →	-0.109	-1.201	.030	.028	3	2
UCEC	ATM →	-0.437	-1.643	.001	.003	3	2
UCEC	Caspase-7-cleavedD198 →	+0.650	+2.267	<.001	<.001	3	2
UCEC	eIF4E →	+0.148	+1.820	.024	.014	3	1
UCEC	Notch1 →	+0.157	+1.893	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

MEK1 by HNRNPUL1 expression — UCEC

Explore this box plot interactively →