HNRNPUL1

Across TCGA cell cohorts, HNRNPUL1 mutation is significantly associated with the RNA expression of many other genes, with 695 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HNRNPUL1-associated genes across cancer lineages are ADAM7, GHRHR, and AHSP. Each is linked with HNRNPUL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPUL1-to-partner and partner-to-HNRNPUL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM7 grouped by HNRNPUL1-low versus HNRNPUL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPUL1→partner) and Y-score (partner→HNRNPUL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ADAM7 →	+0.002	+2.345	<.001	.007	3	2
LUNG_NSCLC_LUSC	GHRHR →	+0.176	+4.643	<.001	.008	3	1
SOFT_TISSUE	AHSP →	+0.202	+4.417	<.001	.004	3	1
SOFT_TISSUE	OR2AJ1 →	+0.009	+4.369	<.001	.008	3	1
SOFT_TISSUE	CCR8 →	+0.019	+4.369	<.001	.008	3	1
SOFT_TISSUE	HBM →	+0.116	+5.169	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 695 associations by consensus.

ADAM7 by HNRNPUL1 expression — LARGE_INTESTINE

Explore this box plot interactively →