HNRNPU

Across TCGA patient cohorts, HNRNPU RNA expression is significantly associated with the protein abundance of many other proteins, with 17,595 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HNRNPU-associated proteins across cancer lineages are IPO9, C1orf35, and DHX9. Each is linked with HNRNPU in more than 8 cancer types. Because this analysis shows association rather than direction, both HNRNPU-to-partner and partner-to-HNRNPU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HNRNPU versus IPO9 in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPU→partner) and Y-score (partner→HNRNPU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IPO9 →	+0.394	+0.423	<.001	<.001	3	9
HNSC	C1orf35 →	+0.429	+0.431	<.001	<.001	3	8
HNSC	DHX9 →	+0.227	+0.641	<.001	<.001	3	8
HNSC	PARP1 →	+0.462	+0.604	<.001	<.001	3	7
HNSC	RCOR3 →	+0.428	+0.628	<.001	<.001	3	7
GBM	KDM1A →	+0.263	+0.258	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,595 associations by consensus.

HNRNPU vs IPO9 — BRCA

Explore this scatter interactively →