HNRNPU

Across TCGA patient cohorts, HNRNPU protein abundance is significantly associated with the RNA expression of many other genes, with 19,953 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HNRNPU-associated genes across cancer lineages are G0S2, USP21, and CCR1. Each is linked with HNRNPU in more than 7 cancer types. Because this analysis shows association rather than direction, both HNRNPU-to-partner and partner-to-HNRNPU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HNRNPU versus G0S2 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPU→partner) and Y-score (partner→HNRNPU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	G0S2 →	-1.496	-0.198	<.001	<.001	3	8
LSCC	USP21 →	+0.654	+0.241	<.001	<.001	3	8
CCRCC	CCR1 →	-1.022	-0.165	<.001	<.001	3	8
HNSC	CNNM3 →	+1.035	+0.257	<.001	<.001	3	8
UCEC	PTAFR →	-1.072	-0.173	<.001	.007	3	8
CCRCC	CXCL8 →	-2.138	-0.135	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,953 associations by consensus.

HNRNPU vs G0S2 — BRCA

Explore this scatter interactively →