HNRNPU

Across TCGA cell cohorts, HNRNPU RNA expression is significantly associated with the go_rna of many other GO terms, with 5,145 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HNRNPU-associated GO terms across cancer lineages are DNA replication, DNA replication initiation, and Lagging strand elongation. Each is linked with HNRNPU in more than 18 cancer types. Because this analysis shows association rather than direction, both HNRNPU-to-partner and partner-to-HNRNPU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by HNRNPU-low versus HNRNPU-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPU→partner) and Y-score (partner→HNRNPU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA replication →	+0.131	+0.990	<.001	<.001	3	19
BONE	DNA replication initiation →	+0.187	+0.683	<.001	<.001	3	19
OESOPHAGUS	Lagging strand elongation →	+0.155	+0.700	<.001	<.001	3	19
BONE	Cell cycle checkpoint signaling →	+0.103	+0.663	.002	.002	3	19
BONE	DNA replication checkpoint signaling →	+0.242	+0.836	<.001	<.001	3	19
OESOPHAGUS	Negative regulation of cell cycle process →	+0.084	+0.420	<.001	.006	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,145 associations by consensus.

DNA replication by HNRNPU expression — SOFT_TISSUE

Explore this box plot interactively →