HNRNPLP2

Across TCGA pan-cancer cohorts, HNRNPLP2 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated HNRNPLP2 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher HNRNPLP2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated HNRNPLP2 expression acts as an unfavorable survival marker, although some lineages such as UVM and THYM show a favorable association.

UVM, KICH, and LIHC are the cancer types where HNRNPLP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.788	0.404	<.001	64	view →
KICH	DFS	Tertile	All	0.591	1.000	<.001	59	view →
LIHC	DFS	Tertile	All	0.346	0.510	.001	38	view →
BLCA	DFS	Quartile	All	0.309	0.478	.009	31	view →
THYM	DFS	Quartile	II,III,IV	1.000	0.481	<.001	30	view →
LGG	DFS	Quartile	All	0.813	0.624	<.001	23	view →
KIRP	DFS	Tertile	II,III,IV	0.928	0.502	.018	20	view →
READ	OS	Median	All	1.000	0.812	.005	20	view →
ACC	DFS	Quartile	All	0.512	0.844	.004	19	view →
HNSC	DFS	Tertile	IV	0.404	0.255	.010	16	view →
SKCM	DFS	Quartile	II,III,IV	0.184	0.402	.003	12	view →
KIRC	OS	Tertile	All	0.694	0.528	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

HNRNPLP2–UVM (DFS)

Open the UVM breakdown →