HNRNPLL

Across TCGA pan-cancer cohorts, HNRNPLL mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HNRNPLL data layer compared with 23 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher HNRNPLL mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HNRNPLL expression acts as an unfavorable survival marker, although some lineages such as GBM and PDAC show a favorable association.

HNSC, UCEC, and GBM are the cancer types where HNRNPLL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.581	0.925	<.001	68	view →
UCEC	DFS	Tertile	III,IV	0.419	1.000	.022	12	view →
GBM	OS	Tertile	All	0.546	0.245	.003	11	view →
CCRCC	OS	Median	All	0.911	1.000	.023	2	view →
PDAC	OS	Tertile	All	0.737	0.502	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

HNRNPLL–HNSC (OS)

Open the HNSC breakdown →