HNRNPK

Across TCGA cell cohorts, HNRNPK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,718 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HNRNPK-associated GO terms across cancer lineages are Regulation of chromosome condensation, Immunoglobulin heavy chain V-D-J recombination, and Spindle elongation. Each is linked with HNRNPK in more than 18 cancer types. Because this analysis shows association rather than direction, both HNRNPK-to-partner and partner-to-HNRNPK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome condensation grouped by HNRNPK-low versus HNRNPK-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPK→partner) and Y-score (partner→HNRNPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of chromosome condensation →	+0.223	+0.613	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Immunoglobulin heavy chain V-D-J recombination →	+0.205	+0.676	.001	.005	3	19
OESOPHAGUS	Spindle elongation →	+0.204	+0.443	.003	.001	3	18
CNS	Protein import into nucleus →	+0.081	+0.309	<.001	<.001	3	18
URINARY_TRACT	Protein localization to chromosome, centromeric region →	+0.134	+0.471	.001	.002	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA damage checkpoint →	+0.093	+0.721	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,718 associations by consensus.

Regulation of chromosome condensation by HNRNPK expression — BREAST

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