HNRNPK

Across TCGA cell cohorts, HNRNPK mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HNRNPK-associated genes across cancer lineages are ETNPPL, HTR1E, and ZBBX. Each is linked with HNRNPK in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPK-to-partner and partner-to-HNRNPK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETNPPL grouped by HNRNPK-low versus HNRNPK-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPK→partner) and Y-score (partner→HNRNPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ETNPPL →	+0.209	+3.758	.003	.004	3	1
LARGE_INTESTINE	HTR1E →	+0.070	+3.345	<.001	.007	3	1
LARGE_INTESTINE	ZBBX →	+0.103	+3.658	.002	.005	3	1
LARGE_INTESTINE	ADIPOQ →	+0.011	+3.632	<.001	.003	3	1
LARGE_INTESTINE	RIPPLY2 →	+0.494	+3.196	<.001	.007	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

ETNPPL by HNRNPK expression — LARGE_INTESTINE

Explore this box plot interactively →