HNRNPH3

Across TCGA pan-cancer cohorts, HNRNPH3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HNRNPH3 data layer compared with 29 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HNRNPH3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated HNRNPH3 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, UCEC, and LSCC are the cancer types where HNRNPH3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.889	.023	18	view →
UCEC	OS	Quartile	II,III,IV	0.523	1.000	.020	8	view →
LSCC	DFS	Quartile	All	0.900	0.561	.010	7	view →
PDAC	DFS	Median	II,III,IV	0.200	0.329	.038	4	view →
LUAD	OS	Median	II,III,IV	0.777	0.492	.030	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

HNRNPH3–COAD (DFS)

Open the COAD breakdown →