HNRNPH3

Across TCGA patient cohorts, HNRNPH3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,741 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HNRNPH3-associated genes across cancer lineages are DDX50, ASXL1, and ELL2. Each is linked with HNRNPH3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HNRNPH3-to-partner and partner-to-HNRNPH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HNRNPH3 versus DDX50 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPH3→partner) and Y-score (partner→HNRNPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDX50 →	+0.500	+0.254	.002	.001	3	6
COAD	ASXL1 →	+0.702	+0.197	<.001	<.001	3	5
OV	ELL2 →	-1.053	-0.226	<.001	.005	3	5
LUAD	AK3P3 →	+0.555	+0.123	.001	.002	3	5
COAD	PRPF6 →	+0.692	+0.155	<.001	<.001	3	4
LSCC	GID8 →	+0.368	+0.165	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,741 associations by consensus.

HNRNPH3 vs DDX50 — OV

Explore this scatter interactively →